circRNA basic information
circBase ID: -
Name: hsa_circ_CDC45
Synonym: -
Host Gene: hsa-miR-516b, hsa-miR-527
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: U87MG, U118, U251, LN229, NHA
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-516b, hsa-miR-527
Biological function: promoted cell proliferation and inhibited apoptosis.
Molecular mechanism: circ-CDC45 sponged and regulated the expression of hsa-miR-516b and hsa-miR-527
Survival: -
Supported No.:
 1
Description:

circ-CDC45 sponged and regulated the expression of miR-516b and miR-527 to promote cell growth and invasion.
Other information
Title:

Overexpression of circular RNA circ-CDC45 facilitates glioma cell progression by sponging miR-516b and miR-527 and predicts an adverse prognosis.

Journal: J Cell Biochem
Published: 2019/8/14
PubMed ID: 31407396