circRNA basic information
circBase ID: hsa_circ_0000977
Name: hsa_circ_NOL10
Synonym: circ_0000977
Host Gene: hsa-miR-153
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human PC cell line (Panc-1, HEK-293)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF1A, ADAM10
Associated microRNA: hsa-miR-153
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

circ_0000977/miR-153 axis modulates HIF1A-mediated immune escape of PC cells through miR-153 downstream targets HIF1A and ADAM10.
Other information
Title:

Hypoxia-induced shedding of MICA and HIF1A-mediated immune escape of pancreatic cancer cells from NK cells: role of circ_0000977/miR-153 axis.

Journal: RNA Biol
Published: 2019/8/14
PubMed ID: 31402756