circRNA basic information
circBase ID: -
Name: rno_circ_GTF2I
Synonym: Circ-GTF2I
Host Gene: rno-miR-590-5p
 
 
 
Disease basic information
DO ID:
1287
DO name: cardiovascular system disease
Disease details: myocardial ischemia-reperfusion injury
Species: rat
Species details: rat
Sample type: PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KBTBD7
Associated microRNA: rno-miR-590-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

CircRNA circ-GTF2I aggravated MIRI and neonatal rat cardiomyocyte damage in vivo and in vitro by regulating miR-590-5p and the heart development transcription factor KBTBD7.

Other information
Title:

Circ-GTF2I/miR-590-5p Axis Aggravates Myocardial Ischemia-Reperfusion Injury by Regulating Kelch Repeat and BTB Domain-Containing Protein 7.

Journal: Evid Based Complement Alternat Med
Published: 2022/6/8
PubMed ID: 35668777