circRNA basic information
circBase ID: -
Name: hsa_circ_SPECC1
Synonym: -
Host Gene: hsa-miR-526b
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: gastric cancer cell lines (AGS, BGC-823, HGC-27, MGC-803, MKN-45, SGC-7901), human gastric epithelial cell line (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: KDM4A/YAP1
Associated microRNA: hsa-miR-526b
Biological function: inhibiting GC cell growth and invasion
Molecular mechanism: enhance hsa-miR-526b inhibitory effect on downstream KDM4A/YAP1 pathway by adsorbing it
Survival: -
Supported No.:
 2
Description:

circ_SPECC1 can enhance miR-526b inhibitory effect on downstream KDM4A/YAP1 pathway by adsorbing it, thus inhibiting GC cell growth and invasion.
Other information
Title:

Circ_SPECC1 enhances the inhibition of miR-526b on downstream KDM4A/YAP1 pathway to regulate the growth and invasion of gastric cancer cells.

Journal: Biochem Biophys Res Commun
Published: 2019/7/28
PubMed ID: 31349968