circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: -
 
 
 
Disease basic information
DO ID:
 219
DO name: colon cancer
Disease details: colon cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: 293T, human colon carcinoma cell lines (SW620, Caco2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PD_L1
Associated microRNA: -
Biological function: -
Molecular mechanism: increases cell surface PD_L1 protein levels
Survival: -
Supported No.:
 1
Description:

CDR1as lead to poor prognosis by increasing cell surface PD_L1 levels through microRNA_7_independent mechanisms.
Other information
Title:

Expression of circular RNA CDR1_AS in colon cancer cells increases cell surface PD_L1 protein levels.

Journal: Oncol Rep
Published: 2019/7/20
PubMed ID: 31322270