circRNA basic information
circBase ID: -
Name: hsa_circ_CRIM1
Synonym: -
Host Gene: hsa-miR-93, hsa-miR-182
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human LUAC cell lines (A549, H1299, H2228, pc9, H1975)
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-93, hsa-miR-182
Biological function: inhibits invasion and metastasis
Molecular mechanism: circCRIM1 could promote the expression of leukemia inhibitory factor receptor, a well-known tumor suppressor, by sponging hsa-miR-93 and hsa-miR-182
Survival: better
Supported No.:
 2
Description:

Our study showed that circCRIM1 inhibits the invasion and metastasis of lung adenocarcinoma cancer cells.
Other information
Title:

Circular RNA circCRIM1 inhibits invasion and metastasis in lung adenocarcinoma through the microRNA (miR)-182/miR-93-leukemia inhibitory factor receptor pathway.

Journal: Cancer Sci
Published: 2019/7/14
PubMed ID: 31301086