circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA-104718
Host Gene: hsa-miR-218-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human HCC cell lines (SMMC-7721, HepG2, MHCC-LM3, SK-Hep1), control hepatic normal cell (L02), HEK293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TXNDC5
Associated microRNA: hsa-miR-218-5p
Biological function: accelerated cell proliferation, migration, invasion, and inhibited apoptosis
Molecular mechanism: target hsa-miR-218-5p/TXNDC5 signaling pathway
Survival: -
Supported No.:
 1
Description:

our results indicate that circRNA-104718 acts as a ceRNA and promotes HCC progression through the targeting of miR-218-5p/TXNDC5 signaling pathway.
Other information
Title:

CircRNA-104718 acts as competing endogenous RNA and promotes hepatocellular carcinoma progression through microRNA-218-5p/TXNDC5 signaling pathway.

Journal: Clin Sci (Lond)
Published: 2019/7/7
PubMed ID: 31278132