circRNA basic information
circBase ID: hsa_circ_0000745
Name: hsa_circ_SPECC1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SiHa, CaSki cells
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cervical cancer by increasing cell proliferation, migration, and invasion
Molecular mechanism: reducing the expression of E-cad
Survival: -
Supported No.:
 2
Description:

As a tumor promoter in CC, hsa_circ_0000745 enhances the cells ability to proliferate, migrate, and invade by reducing the expression of E-cad.
Other information
Title:

hsa_circ_0000745 promotes cervical cancer by increasing cell proliferation, migration, and invasion.

Journal: J Cell Physiol
Published: 2019/7/1
PubMed ID: 31256433