circRNA basic information
circBase ID: -
Name: hsa_circ_AGFG1
Synonym: -
Host Gene: hsa-miR-203
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZNF281
Associated microRNA: hsa-miR-203
Biological function: promote EMT and metastasis
Molecular mechanism: sponges hsa-miR-203 to upregulating ZNF281 expression.
Survival: -
Supported No.:
 2
Description:

our study suggests that circAGFG1 promotes NSCLC growth and metastasis though a circAGFG1/miR-203/ZNF281 axis and may represent a novel therapeutic target.
Other information
Title:

CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.

Journal: Thorac Cancer
Published: 2019/6/28
PubMed ID: 31243884