circRNA basic information
circBase ID: -
Name: hsa_circ_ANKS1B
Synonym: -
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human intestinal epithelial cells (HIEC), human colorectal cancer cell lines (SW480, LoVo, HT29, SW480, Caco-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXM1
Associated microRNA: hsa-miR-149
Biological function: promotes cell migration and invasion
Molecular mechanism: acting as a molecular sponge of hsa-miR-149 to modulate FOXM1 and Slug protein levels
Survival: -
Supported No.:
 1
Description:

circANKS1B promotes colorectal cancer cell migration and invasion by acting as a molecular sponge of miR-149 to modulate FOXM1 and Slug protein levels.
Other information
Title:

circANKS1B regulates FOXM1 expression and promotes cell migration and invasion by functioning as a sponge of the miR-149 in colorectal cancer.

Journal: Onco Targets Ther
Published: 2019/6/20
PubMed ID: 31213828