circRNA basic information
circBase ID: -
Name: hsa_circ_RAD23B
Synonym: circRAD23B
Host Gene: hsa-miR-5095
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal esophageal epithelial cell line (HEEC), human esophageal cancer cell lines (EC109, KYSE-150, TE-1, TE-10), human gastric cancer cell line (HGC-27), human hepatocarcinoma cell line (HepG2), human breast cancer cell line (MDA-MB-231), human embryonic kidney cell line (HEK-293T), human keratinocyte cell line (HaCaT), human lung cancer cell line (A549)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-5095
Biological function: facilitates proliferation and invasion
Molecular mechanism: facilitated expression of PARP2 and AKT2 by sponging hsa-miR-5095
Survival: -
Supported No.:
 1
Description:

In summary, these data displayed the crucial role of circRAD23B/miR-5095 regulating PARP2 and AKT2 in esophageal cancer, and provided a novel mechanism in the pathogenesis of esophageal cancer.
Other information
Title:

CircRAD23B facilitates proliferation and invasion of esophageal cancer cells by sponging miR-5095.

Journal: Biochem Biophys Res Commun
Published: 2019/6/19
PubMed ID: 31208717