circRNA basic information
circBase ID: hsa_circ_0001946
Name: hsa_circ_CDR1
Synonym: ciRS-7, CDR1as
Host Gene: hsa-miR-135b-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ovarian cancer cell lines (HO8910, A2780)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-135b-5p
Biological function: inhibited the proliferation, invasion and migration
Molecular mechanism: acting as a sponge of hsa-miR-135b-5p, promotes the expression of HIF1AN
Survival: -
Supported No.:
 3
Description:

CDR1as, acting as a sponge of miR-135b-5p, promotes the expression of HIF1AN and therefore plays a role in tumor inhibition.
Other information
Title:

Circular RNA CDR1as acts as a sponge of miR-135b-5p to suppress ovarian cancer progression.

Journal: Onco Targets Ther
Published: 2019/6/14
PubMed ID: 31190886