circRNA basic information
circBase ID: hsa_circ_0047905
Name: hsa_circ_SERPINB5
Synonym: circRNA0047905
Host Gene: hsa-miR-4516, hsa-miR-1227-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: 293T cell, human GC cell line (AGS)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-4516, hsa-miR-1227-5p
Biological function: initiating gastric cancer progression
Molecular mechanism: circRNA0047905 directly binds miR4516 and miR1227-5p, relieving suppression for targets SERPINB5 and MMP11
Survival: -
Supported No.:
 2
Description:

We investigated the possibility that circular RNA 0047905 (circRNA0047905) might act as a tumor promoter in the pathogenesis of gastric cancer by profiling miRNA expression in GC tissues and paired noncancerous mucosa tissues using miRNA microarrays.
Other information
Title:

Circular RNA 0047905 acts as a sponge for microRNA4516 and microRNA1227-5p, initiating gastric cancer progression.

Journal: Cell Cycle
Published: 2019/6/4
PubMed ID: 31157588