circRNA basic information
circBase ID: -
Name: hsa_circ_ACC1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
3350
DO name: mesenchymal cell neoplasm
Disease details: metabolic stress
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCT116, 293T, HeLa, A549, HepG2, HT29, U2OS, H1299, MCF7, Hep3B, HAFF, LO2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: promotes cell proliferation
Molecular mechanism: elicit AMPK activation
Survival: -
Supported No.:
1
Description:

We conclude that circACC1 serves as an economic means to elicit AMPK activation and moreover propose that cancer cells exploit circACC1 during metabolic reprogramming.

Other information
Title:

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.

Journal: Cell Metab
Published: 2019/6/4
PubMed ID: 31155494