circRNA basic information
circBase ID: hsa_circ_0079593
Name: hsa_circ_IGF2BP3
Synonym: circ_0079593
Host Gene: hsa-miR-182, hsa-miR-433
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: glioma cells (U118, U251, U87MG, LN229), normal human astrocytes cell line (NHA)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-182, hsa-miR-433
Biological function: facilitates cell growth and invasion
Molecular mechanism: sponging hsa-miR-182 and hsa-miR-433
Survival: poor
Supported No.:
 3
Description:

microRNA 182 (miR-182) and miR-433 could be sponged and negatively regulated by circ_0079593. Further, rescue assays demonstrated that the biological functions of circ_0079593 are dependent on its inhibition of miR-182 and miR-433.
Other information
Title:

Circular RNA circ_0079593 indicates a poor prognosis and facilitates cell growth and invasion by sponging miR-182 and miR-433 in glioma.

Journal: J Cell Biochem
Published: 2019/5/31
PubMed ID: 31148222