circRNA basic information
circBase ID: -
Name: -
Synonym: mm9-circ-012559
Host Gene: mmu-miR-223
 
 
 
Disease basic information
DO ID:
 6000
DO name: congestive heart failure
Disease details: congestive heart failure
Species: mouse
Species details: mouse
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ARC
Associated microRNA: mmu-miR-223
Biological function: inhibit cardiac hypertrophy and heart failure
Molecular mechanism: participate in pathway that is composed of HRCR, mmu-miR-223, and ARC; miRNA sponge
Survival: -
Supported No.:
 1
Description:

Heart-related circRNA inhibits cardiomyocytes hypertrophy through targeting miR-223 and apoptosis repressor with CARD domain.
Other information
Title:

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223.

Journal: Eur Heart J
Published: 2016/1/24
PubMed ID: 26802132