circRNA basic information
circBase ID: hsa_circ_0008035
Name: hsa_circ_EXT1
Synonym: -
Host Gene: hsa-miR-375
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: gastric cancer cells (BGC-823, MGC-803, AGS, SGC-7901), normal cells (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: miR-375, YBX1
Associated microRNA: hsa-miR-375
Biological function: promote proliferation and invasion
Molecular mechanism: targeting the hsa-miR-375/YBX1 axis
Survival: -
Supported No.:
 4
Description:

hsa_circ_0008035 acted as a sponge for the miR-375 and absorbed its expression, and miR-375 was found to target YBX1 3-UTR, constructing a hsa_circ_0008035/miR-375/YBX1 axis.
Other information
Title:

A novel circular RNA hsa_circ_0008035 contributes to gastric cancer tumorigenesis through targeting the miR-375/YBX1 axis.

Journal: Am J Transl Res
Published: 2019/5/21
PubMed ID: 31105852