circRNA basic information
circBase ID: hsa_circ_0023404
Name: hsa_circ_RNF121
Synonym: -
Host Gene: hsa-miR-5047
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human cervical cancer cells (HeLa, SiHa), 293 T cell
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: VEGFA
Associated microRNA: hsa-miR-5047
Biological function: facilitate invasion
Molecular mechanism: hsa_circ_0023404 and VEGFA were upregulated and showed positive correlation in cervical tumors, while hsa-miR-5047 was downregulated and showed negative correlation with hsa_circ_0023404 and VEGFA.
Survival: -
Supported No.:
 3
Description:

we reveal a novel role of hsa_circ_0023404 for cervical cancer metastasis and chemoresistance by regulating miR-5047.
Other information
Title:

Hsa_circ_0023404 enhances cervical cancer metastasis and chemoresistance through VEGFA and autophagy signaling by sponging miR-5047.

Journal: Biomed Pharmacother
Published: 2019/5/15
PubMed ID: 31082770