circRNA basic information
circBase ID: hsa_circ_0007919
Name: -
Synonym: -
Host Gene: hsa-miR-138
 
 
 
Disease basic information
DO ID:
8577
DO name: ulcerative colitis
Disease details: ulcerative colitis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A colorectal cancer cell line Caco2 and a normal-derived colon mucosa cell line NCM460
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-138
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

Hsa_circ_0007919 was reduced persistently after inflammatory treatments, and it was relevant to Mayo endoscopic subscores and the expression of tight junction molecules. Finally, hsa_circ_0007919 could harbor miR-138, and let-7a to regulate the targeted mRNAs EPC1 and VIPR1.

Other information
Title:

Integrated analysis of circRNAs and mRNAs expression profile revealed the involvement of hsa_circ_0007919 in the pathogenesis of ulcerative colitis.

Journal: J Gastroenterol
Published: 2019/5/1
PubMed ID: 31037450