circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: circ-ZNF609
Host Gene: hsa-miR-150-5p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal nasopharyngeal epithelial cell line (NP69), NPC cell lines (5-8F, HONE-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-150-5p
Biological function: promotes growth and metastasis
Molecular mechanism: adsorbs microRNA-150-5p to upregulate Sp1 expression
Survival: -
Supported No.:
 5
Description:

Highly expressed circ-ZNF609 adsorbs microRNA-150-5p to upregulate Sp1 expression, thereby promoting the proliferation and metastatic ability of NPC cells.
Other information
Title:

CircRNA ZNF609 promotes growth and metastasis of nasopharyngeal carcinoma by competing with microRNA-150-5p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/4/20
PubMed ID: 31002133