circRNA basic information
circBase ID: hsa_circ_0007874
Name: hsa_circ_MTO1
Synonym: -
Host Gene: hsa-miR-17
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: QKI-5
Associated microRNA: hsa-miR-17
Biological function: suppresses cell proliferation
Molecular mechanism: circ-MTO1/hsa-miR-17/QKI-5
Survival: better
Supported No.:
 1
Description:

our data suggest that circ-MTO1 is a critical negative regulator of LUAD and elucidate the potential molecular mechanism of a novel circ-MTO1/miR-17/QKI-5 feedback loop in inhibiting LUAD progression.
Other information
Title:

A regulatory circuit of circ-MTO1/miR-17/QKI-5 inhibits the proliferation of lung adenocarcinoma.

Journal: Cancer Biol Ther
Published: 2019/4/13
PubMed ID: 30975029