circRNA basic information
circBase ID: -
Name: hsa_circ_TADA2A
Synonym: -
Host Gene: hsa-miR-203a-3p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HEK-293, human osteoblast (hFOB1.19), human OS cells (HOS, 143B, MG-63, U2OS, SJSA-1)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-203a-3p
Biological function: facilitated cell proliferation, migratory and invasive capacities
Molecular mechanism: circTADA2A could readily sponge hsa-miR-203a-3p to upregulate the expression of CREB3
Survival: -
Supported No.:
 2
Description:

CircTADA2A functions as a tumor promoter in OS to increase malignant tumor behavior through the miR-203a-3p/CREB3 axis.
Other information
Title:

Circular RNA circTADA2A promotes osteosarcoma progression and metastasis by sponging miR-203a-3p and regulating CREB3 expression.

Journal: Mol Cancer
Published: 2019/4/4
PubMed ID: 30940151