circRNA basic information
circBase ID: -
Name: -
Synonym: RNA ciRS-7
Host Gene: hsa-miR-7
 
 
 
Disease basic information
DO ID:
 1793
DO name: pancreatic cancer
Disease details: pancreatic cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: BXPC-3, PANC-1, HPC-Y5
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EGFR, STAT3
Associated microRNA: hsa-miR-7
Biological function: promotes the proliferation and metastasis
Molecular mechanism: regulating hsa-miR-7-mediated EGFR/STAT3 signaling pathway
Survival: poor
Supported No.:
 1
Description:

Circular RNA ciRS-7 plays an oncogene role in PDAC, partly by targeting miR-7 and regulating the EGFR/STAT3 signaling pathway.
Other information
Title:

Circular RNA ciRS-7 promotes the proliferation and metastasis of pancreatic cancer by regulating miR-7-mediated EGFR/STAT3 signaling pathway.

Journal: Hepatobiliary Pancreat Dis Int
Published: 2019/3/23
PubMed ID: 30898507