circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-193a-3p
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human prostate epithelial cell line (RWPE-1), PCa cell lines (LNCaP, PC3, DU145, 22Rv1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MCL1
Associated microRNA: hsa-miR-193a-3p
Biological function: promotes cell proliferation and invasion
Molecular mechanism: sponging hsa-miR-193a-3p and regulating MCL1 expression
Survival: -
Supported No.:
 4
Description:

The circHIPK3-mediated miR-193a-3p-MCL1 signaling promotes PCa development and progression, providing a novel therapeutic target for PCa.
Other information
Title:

Circular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression.

Journal: Cancer Manag Res
Published: 2019/3/14
PubMed ID: 30863152