circRNA basic information
circBase ID: -
Name: hsa_circ_SETD3
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HepG2, Hep3B, Huh7, HCCLM3, SK-Hep1, PLC, LO2, 293 T
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: SETD3
Associated microRNA: -
Biological function: inhibiting hepatocellular carcinoma growth
Molecular mechanism: circSETD3/hsa-miR-421/MAPK14 pathway
Survival: -
Supported No.:
 1
Description:

CircSETD3 is a novel tumour suppressor of HCC and is a valuable prognostic biomarker. Moreover, circSETD3 inhibits the growth of HCC partly through the circSETD3/miR-421/MAPK14 pathway.
Other information
Title:

CircSETD3 (Hsa_circ_0000567) acts as a sponge for microRNA-421 inhibiting hepatocellular carcinoma growth.

Journal: J Exp Clin Cancer Res
Published: 2019/2/24
PubMed ID: 30795787