circRNA basic information
circBase ID: hsa_circ_0005397
Name: hsa_circ_RHOT1
Synonym: -
Host Gene: hsa-miR-26b-3p, hsa-miR-125a-3p, hsa-miR-181a-3p, hsa-miR-330-5p, hsa-miR-382-5p
 
 
 
Disease basic information
DO ID:
 3498
DO name: pancreatic ductal adenocarcinoma
Disease details: pancreatic ductal adenocarcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-26b-3p, hsa-miR-125a-3p, hsa-miR-181a-3p, hsa-miR-330-5p, hsa-miR-382-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

To verify the microarray data, we randomly selected seven differentially expressed circRNAs, including two up-regulated circRNAs and five down-regulated circRNAs (including hsa_circ_0001946, hsa_circ_0005397, hsa_circ_0006913, hsa_circ_0000257, hsa_circ_0005785, hsa_circ_0041150, and hsa_circ_0008719). We validated their expression levels via qRT-PCR in 20 sets of PDAC tissues and adjacent normal tissues. We found that the expression patterns of seven circRNAs were consistent with the microarray data.
Other information
Title:

Circular RNA Expression Profile of Pancreatic Ductal Adenocarcinoma Revealed by Microarray.

Journal: Cell Physiol Biochem
Published: 2016/12/21
PubMed ID: 27997903