circRNA basic information
circBase ID: -
Name: hsa_circ_TFRC
Synonym: cTFRC
Host Gene: hsa-miR-107
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: bladder cancer cell lines (EJ, T24, 5637, UMUC3, BIU87, J82, SW780), bladder normal epithelial cell (HCV29)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TFRC
Associated microRNA: hsa-miR-107
Biological function: promote invasion and proliferation
Molecular mechanism: acts as a competing endogenous RNA (ceRNA) for hsa-miR-107 to regulate TFRC expression
Survival: poor
Supported No.:
 1
Description:

The cTFRC may exert regulatory functions in BC and may be a potential marker of BC diagnosis or progression.
Other information
Title:

Circular RNA cTFRC acts as the sponge of MicroRNA-107 to promote bladder carcinoma progression.

Journal: Mol Cancer
Published: 2019/2/21
PubMed ID: 30782157