circRNA basic information
circBase ID: -
Name: hsa_circ_PSMC3
Synonym: circPSMC3
Host Gene: hsa-miR-296-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human gastric cancer cell lines (BGC823, MGC803, SGC7901, AGS, MKN45)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-296-5p
Biological function: suppresses the proliferation and metastasis
Molecular mechanism: sponging hsa-miR-296-5p
Survival: -
Supported No.:
 1
Description:

Our study reveals that circPSMC3 can serve as a novel potential circulating biomarker for detection of GC. CircPSMC3 participates in progression of gastric cancer by sponging miRNA-296-5p with PTEN, providing a new insight into the treatment of gastric cancer.
Other information
Title:

CircPSMC3 suppresses the proliferation and metastasis of gastric cancer by acting as a competitive endogenous RNA through sponging miR-296-5p.

Journal: Mol Cancer
Published: 2019/2/20
PubMed ID: 30777076