circRNA basic information
circBase ID: hsa_circ_0074027
Name: hsa_circ_PITX1
Synonym: circ_0074027
Host Gene: hsa-miR-518a-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NHA cell, human GBM cell lines (U87, U251, A172, LN229)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IL17RD
Associated microRNA: hsa-miR-518a-5p
Biological function: promotes glioblastoma cell growth and invasion
Molecular mechanism: circ_0074027 could sponge hsa-miR-518a-5p to release its suppression on IL17RD
Survival: -
Supported No.:
 3
Description:

The circ_0074027 plays an oncogenic role in GBM by regulating miR-518a-5p/IL17RD signaling.
Other information
Title:

Upregulated circular RNA circ_0074027 promotes glioblastoma cell growth and invasion by regulating miR-518a-5p/IL17RD signaling pathway.

Journal: Biochem Biophys Res Commun
Published: 2019/2/11
PubMed ID: 30738578