circRNA basic information
circBase ID: -
Name: -
Synonym: circOMA1
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 3829
DO name: pituitary adenoma
Disease details: pituitary adenoma
Species: human
Species details: human
Sample type: cell line
Sample type details: pituitary tumor derived folliculostellate cell line (PDFS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TPT1
Associated microRNA: hsa-miR-145-5p
Biological function: facilitate cell growth and invasion
Molecular mechanism: acting as the sponge of tumor suppressor hsa-miR-145-5p to regulate the TPT1 signaling pathway
Survival: -
Supported No.:
 1
Description:

CircOMA1 promotes NFPA progression by acting as the sponge of tumor suppressor miR-145-5p to regulate the TPT1 signaling pathway, revealing a therapeutic target in preventing the tumorigenesis of NFPAs.
Other information
Title:

circOMA1-Mediated miR-145-5p Suppresses Tumor Growth of Nonfunctioning Pituitary Adenomas by Targeting TPT1.

Journal: J Clin Endocrinol Metab
Published: 2019/2/6
PubMed ID: 30721952