circRNA basic information
circBase ID: -
Name: hsa_circ_LRP6
Synonym: circ_Lrp6
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 178
DO name: vascular disease
Disease details: vascular disease
Species: human
Species details: human
Sample type: cell line
Sample type details: HEK293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-145
Biological function: -
Molecular mechanism: Regulating miRNA-145
Survival: -
Supported No.:
 1
Description:

The circ_Lrp6 is an intracellular modulator and a natural sponge for miR-145, counterbalancing the functions of the miRNA in VSMCs.
Other information
Title:

Circ_Lrp6, a Circular RNA Enriched in Vascular Smooth Muscle Cells, Acts as a Sponge Regulating miRNA-145 Function.

Journal: Circ Res
Published: 2018/12/26
PubMed ID: 30582454