circRNA basic information
circBase ID: -
Name: hsa_circ_NF1
Synonym: -
Host Gene: hsa-miR-16
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human GC cell lines (MKN28, NCI-N87, AGS, KATOIII, RF1, RF48), normal gastric epithelial cell line (HFE145)
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-16
Biological function: promote proliferation
Molecular mechanism: binds to hsa-miR-16, thereby derepressing its downstream target mRNAs, MAP7 and AKT3
Survival: -
Supported No.:
 1
Description:

The circNF1 acts as a novel oncogenic circRNA in GC by functioning as a miR-16 sponge.
Other information
Title:

Novel circular RNA circNF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16.

Journal: Endocr Relat Cancer
Published: 2018/12/24
PubMed ID: 30576282