circRNA basic information
circBase ID: -
Name: hsa_circ_AMOTL1L
Synonym: -
Host Gene: hsa-miR-193a
 
 
 
Disease basic information
DO ID:
 10283
DO name: prostate cancer
Disease details: prostate cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: PC3, LNCaP, DU145, RWPE-1
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: RBM25, p53
Associated microRNA: hsa-miR-193a
Biological function: suppresses cell migration and invasion
Molecular mechanism: circAMOTL1L-hsa-miR-193a-5p-Pcdha pathway.
Survival: -
Supported No.:
 1
Description:

These findings have linked p53/RBM25-mediated circAMOTL1L-miR-193a-5p-Pcdha regulatory axis to EMT in metastatic progression of PCa.
Other information
Title:

Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway.

Journal: Oncogene
Published: 2018/12/12
PubMed ID: 30531834