circRNA basic information
circBase ID: -
Name: hsa_circ_PUM1
Synonym: circPUM1
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: 16HBE, 293T, A549, SPC-A1, H1975
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Cyclin D1, Bcl-2
Associated microRNA: hsa-miR-326
Biological function: promoted cell proliferation, migration and invasion while inhibits apoptosis
Molecular mechanism: circPUM1/hsa-miR-326/Cyclin D1 and Bcl-2 axis
Survival: -
Supported No.:
 2
Description:

This present study revealed that circPUM1 functions as an oncogene to promote the tumorigenesis of lung adenocarcinoma through circPUM1/miR-326/Cyclin D1 and Bcl-2 axis.
Other information
Title:

CircPUM1 promotes the malignant behavior of lung adenocarcinoma by regulating miR-326.

Journal: Biochem Biophys Res Commun
Published: 2018/12/12
PubMed ID: 30528736