circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1
Synonym: -
Host Gene: hsa-miR-375
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human cell line (hFOB1.19), human osteosarcoma cell lines (MG-63, u2os, SJSA-1, HOS, 143B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YAP1
Associated microRNA: hsa-miR-375
Biological function: promote proliferation, migration, and invasion
Molecular mechanism: sponges hsa-miR-375 to promote the expression of Yes-associated protein 1
Survival: -
Supported No.:
 2
Description:

circFAT1 contains a binding site for the microRNA-375 (miR-375) and can abundantly sponge miR-375 to upregulate the expression of Yes-associated protein 1.
Other information
Title:

CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells.

Journal: Mol Cancer
Published: 2018/12/6
PubMed ID: 30514309