circRNA basic information
circBase ID: -
Name: hsa_circ_SFMBT2
Synonym: circ-SFMBT2
Host Gene: hsa-miR-182-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human GC cell lines (MKN-45, BGC-823, MGC-803, SGC7901, AGS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CREB1
Associated microRNA: hsa-miR-182-5p
Biological function: promotes the proliferation
Molecular mechanism: competitively sharing hsa-miR-182-5p with CREB1
Survival: poor
Supported No.:
 4
Description:

Our study reveals that circ-SFMBT2 participates in progression of gastric cancer by competitively sharing miR-182-5p with CREB1, providing a novel target to improve the treatment of gastric cancer.
Other information
Title:

Circ-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression.

Journal: Cancer Manag Res
Published: 2018/12/5
PubMed ID: 30510446