circRNA basic information
circBase ID: hsa_circ_0005230
Name: hsa_circ_DNM3OS
Synonym: circ_0005230
Host Gene: hsa-miR-618
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cells (MCF7, SKBR3, BT-20, T47D, MDA-MB-231, MDA-MB-436), normal mammary epithelial cell line (MCF10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CBX8
Associated microRNA: hsa-miR-618
Biological function: promote proliferation, migration, and invasion
Molecular mechanism: promote proliferation, migration, and invasion
Survival: poor
Supported No.:
 1
Description:

circ_0005230/miR-618/CBX8 axis might play a key role in BC tumorigenesis and development.
Other information
Title:

Increased Expression of Circular RNA circ_0005230 Indicates Dismal Prognosis in Breast Cancer and Regulates Cell Proliferation and Invasion via miR-618/ CBX8 Signal Pathway.

Journal: Cell Physiol Biochem
Published: 2018/12/7
PubMed ID: 30504704