circRNA basic information
circBase ID: hsa_circ_0067835
Name: hsa_circ_IFT80
Synonym: circRNA-0067835
Host Gene: hsa-miR-155
 
 
 
Disease basic information
DO ID:
 3328
DO name: temporal lobe epilepsy
Disease details: temporal lobe epilepsy
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human neuroblastoma cells (SH-SY5Y), human embryonic kidney 293 cells (HEK293)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: FOXO3a
Associated microRNA: hsa-miR-155
Biological function: -
Molecular mechanism: acting as a sponge of hsa-miR-155 to promote FOXO3a expression
Survival: -
Supported No.:
 1
Description:

circRNA-0067835 regulated refractory epilepsy progression by acting as a sponge of miR-155 to promote FOXO3a expression, indicating that circRNA-0067835 may serve as a potential therapeutic target for patients with TLE.
Other information
Title:

Comprehensive Circular RNA Profiling Reveals the Regulatory Role of the CircRNA-0067835/miR-155 Pathway in Temporal Lobe Epilepsy.

Journal: Cell Physiol Biochem
Published: 2018/11/30
PubMed ID: 30485839