circRNA basic information
circBase ID: hsa_circ_0067835
Name: hsa_circ_IFT80
Synonym: circRNA-0067835
Host Gene: hsa-miR-155
 
 
 
Disease basic information
DO ID:
 409
DO name: liver disease
Disease details: liver fibrosis
Species: human
Species details: human
Sample type: cell line
Sample type details: LX-2, HEK-293
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: FOXO3a
Associated microRNA: hsa-miR-155
Biological function: promoted cell proliferation while inhibits apoptosis
Molecular mechanism: acting as a sponge of hsa-miR-155 to promote FOXO3a
Survival: -
Supported No.:
 1
Description:

Our experiments showed that circRNA-0067835 regulated liver fibrosis progression by acting as a sponge of miR-155 to promote FOXO3a expression, indicating that circRNA-0067835 may serve as a potential therapeutic target for patients with liver fibrosis.
Other information
Title:

Thymosin-beta4 Mediates Hepatic Stellate Cell Activation by Interfering with CircRNA-0067835/miR-155/FoxO3 Signaling Pathway.

Journal: Cell Physiol Biochem
Published: 2018/11/28
PubMed ID: 30481761