circRNA basic information
circBase ID: -
Name: hsa_circ_FNDC3B
Synonym: -
Host Gene: hsa-miR-1178-3p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human invasive BC cell lines (T24, UM-UC-3), human immortalized uroepithelium cell line (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: G3BP2, SRC, FAK
Associated microRNA: hsa-miR-1178-3p
Biological function: inhibited proliferation, migration and invasion
Molecular mechanism: circFNDC3B acted as a hsa-miR-1178-3p sponge to suppress G3BP2, thereby inhibiting the downstream SRC/FAK signaling pathway
Survival: -
Supported No.:
 2
Description:

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis.
Other information
Title:

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis.

Journal: Mol Cancer
Published: 2018/11/22
PubMed ID: 30458784