circRNA basic information
circBase ID: -
Name: hsa_circ_CCDC66
Synonym: cir-CCDC66
Host Gene: hsa-miR-488-3p
 
 
 
Disease basic information
DO ID:
 10487
DO name: Hirschsprung disease
Disease details: hirschsprung disease
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: 293T, SH_SY5Y
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: DCX
Associated microRNA: hsa-miR-488-3p
Biological function: inhibit cells proliferation and migration
Molecular mechanism: sponging hsa-miR-488-3p
Survival: -
Supported No.:
 1
Description:

This is the first report revealing that cir-CCDC66 modulates DCX expression through sponging miR-488-3p and thus participates in the onset of HSCR.
Other information
Title:

Circular RNA CCDC66 targets DCX to regulate cell proliferation and migration by sponging miR-488-3p in Hirschsprung disease.

Journal: J Cell Physiol
Published: 2018/11/18
PubMed ID: 30443988