circRNA basic information
circBase ID: -
Name: hsa_circ_ABCB10
Synonym: -
Host Gene: hsa-miR-1252
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: breast cancer cell lines (A549, H1975, PC9, H1299, H1650), normal human lung epithelial cells (BEAS_2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXR2
Associated microRNA: hsa-miR-1252
Biological function: promotes cell proliferation and migration
Molecular mechanism: increased FOXR2 levels by sponging hsa-miR-1252
Survival: -
Supported No.:
 4
Description:

The circABCB10 acted as a tumor promoter through a novel miR-1252/FOXR2 axis, providing potential biomarkers and therapeutic targets for the management of NSCLC.
Other information
Title:

CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR-1252/FOXR2 axis.

Journal: J Cell Biochem
Published: 2018/11/13
PubMed ID: 30417418