circRNA basic information
circBase ID: -
Name: -
Synonym: ciRS-133
Host Gene: hsa-miR-133
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric adenocarcinoma cell (SGC7901), HEK293T, 3T3L1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PRDM16
Associated microRNA: hsa-miR-133
Biological function: promotes white adipose browning
Molecular mechanism: promoting the differentiation of preadipocytes into brown-like cells by activating PRDM16 and suppressing hsa-miR-133
Survival: -
Supported No.:
 1
Description:

Exosome-delivered circRNAs are involved in WAT browning and play a key role in cancer-associated cachexia.
Other information
Title:

Exosomal circRNA derived from gastric tumor promotes white adipose browning by targeting the miR-133/PRDM16 pathway.

Journal: Int J Cancer
Published: 2018/11/10
PubMed ID: 30412280