circRNA basic information
circBase ID: hsa_circ_0001721
Name: hsa_circ_CDK14
Synonym: -
Host Gene: hsa-miR-569, hsa-miR-599
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human bone cell line (hFOB1.19), human OS cell lines (HOS, Saos2, MG63, U2OS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-569, hsa-miR-599
Biological function: facilitates cell progression
Molecular mechanism: sponging hsa-miR-569 and hsa-miR-599.
Survival: poor
Supported No.:
 5
Description:

The present data reveal the participation of circ_0001721 in tumorigenesis of OS cells, and may indicate a novel therapeutic target.
Other information
Title:

Upregulation of circular RNA circ_0001721 predicts unfavorable prognosis in osteosarcoma and facilitates cell progression via sponging miR-569 and miR-599.

Journal: Biomed Pharmacother
Published: 2018/11/6
PubMed ID: 30396080