circRNA basic information
circBase ID: hsa_circ_0067934
Name: hsa_circ_PRKCI
Synonym: circ_0067934
Host Gene: hsa-miR-545
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: CC cell lines (SiHa, CaSki, Hela, C4_1), immortalized cervical epithelium cell line (NC104)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EIF3C
Associated microRNA: hsa-miR-545
Biological function: promote cell proliferation, migration, and invasion
Molecular mechanism: hsa-miR-545/EIF3C axis
Survival: poor
Supported No.:
 1
Description:

Our findings revealed that circ_0067934 promotes CC progression via miR-545/EIF3C axis. Our study may provide a new insight into the pathogenesis of CC.
Other information
Title:

Overexpressed circ_0067934 acts as an oncogene to facilitate cervical cancer progression via the miR-545/EIF3C axis.

Journal: J Cell Physiol
Published: 2018/10/27
PubMed ID: 30362562