circRNA basic information
circBase ID: hsa_circ_0058063
Name: hsa_circ_ATIC
Synonym: circ_0058063
Host Gene: hsa-miR-145-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cell lines (T24, J82)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CDK6
Associated microRNA: hsa-miR-145-5p
Biological function: promote cell proliferation, migration and inhibit cell apoptosis
Molecular mechanism: repressed hsa-miR-145-5p, which inhibited the expression of CDK6
Survival: -
Supported No.:
 3
Description:

Circ_0058063 acted as a sponge of miR-145-5p to promote BC progression by regulating CDK6 expression, which provided some potential targets for BC treatment.
Other information
Title:

Circ_0058063 regulates CDK6 to promote bladder cancer progression by sponging miR-145-5p.

Journal: J Cell Physiol
Published: 2018/10/27
PubMed ID: 30362519