circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-124
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: lung cancer cells (A549), normal lung epithelial cells (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-124
Biological function: promote cell proliferation and inhibit cell apoptosis
Molecular mechanism: promote cell proliferation and inhibit cell apoptosis
Survival: -
Supported No.:
 4
Description:

These observations indicate a possible novel therapeutic strategy involving circHIPK3-miR-124 pathway against lung cancer.
Other information
Title:

Circular RNA HIPK3 exerts oncogenic properties through suppression of miR-124 in lung cancer.

Journal: Biochem Biophys Res Commun
Published: 2018/10/26
PubMed ID: 30352682