circRNA basic information
circBase ID: hsa_circ_0001846
Name: hsa_circ_UBAP2
Synonym: circ-UBAP2
Host Gene: hsa-miR-661
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: breast cancer cells (MCF-10A, T47D, BT-20, SK-BR3, MCF-7, MDA-MB-468, MDA-MB-231)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: MTA1
Associated microRNA: hsa-miR-661
Biological function: promote cell proliferation, migration and inhibit cell apoptosis
Molecular mechanism: sponging miRNA-661 to increase the expression of the oncogene MTA1
Survival: poor
Supported No.:
 1
Description:

Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.
Other information
Title:

Upregulation of circ-UBAP2 predicts poor prognosis and promotes triple-negative breast cancer progression through the miR-661/MTA1 pathway.

Journal: Biochem Biophys Res Commun
Published: 2018/10/14
PubMed ID: 30314706